Selleck製品は、NatureやScience等の権威ある科学雑誌に掲載された論文中で数多く使用されています。
- Nature, 2021, 10.1038/s41586-021...
- Nature, 2021, 10.1038/s41586-021...
- Nature, 2021, 600(7890):731-736
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- Nature, 2021, 599(7886):667-672
- Nature, 2021, 599(7884):308-314
- Nature, 2021, 599(7884):302-307
- Nature, 2021, 598(7881):483-488
- Nature, 2021, 10.1038/s41586-021...
- Nature, 2021, 599(7886):679-683
- Nature, 2021, 598(7881):510-514
- Nature, 2021, 597(7875):263-267
- Nature, 2021, 595(7869):730-734
- Nature, 2021, 595(7868):596-599
- Nature, 2021, 10.1038/s41586-021...
- Nature, 2021, 596(7871):262-267
- Nature, 2021, 592(7856):789-793
- Nature, 2021, 593(7858):275-281
- Nature, 2021, 594(7863):442-447
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- Nature, 2021, 590(7846):492-497
- Nature, 2021, 590(7844):129-133
- Nature, 2021, 591(7851):627-632
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- Nature, 2021, 10.1038/s41586-021...
- Nature, 2021, 591(7849):288-292
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- Nature, 2021, 590(7844):151-156
- Nature, 2020, 588(7838):509-514
- Nature, 2020, 588(7838):491-497
- Nature, 2020, 588(7838):479-484
- Nature, 2020, 588(7836):164-168
- Nature, 2020, 588(7836):157-163
- Nature, 2020, 588(7836):130-134
- Nature, 2020, 587(7835):626-631
- Nature, 2020, 586(7829):434-439
- Nature, 2020, 586(7828):292-298
- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 10.1038/s41586-020...
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- Nature, 2020, 585(7825):426-432
- Nature, 2020, 585(7824):283-287
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- Nature, 2020, 586(7827):101-107
- Nature, 2020, 584(7822):608-613
- Nature, 2020, doi: 10.1038/s41586...
- Nature, 2020, 583(7818):845-851
- Nature, 2020, 583(7818):852-857
- Nature, 2020, 580(7801):124-129
- Nature, 2020, 580(7803):391-395
- Nature, 2020, 582(7811):289-293
- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 580(7804):517-523
- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 578(7795):444-448
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- Nature, 2020, 579(7797):118-122
- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 577(7788):109-114
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- Nature, 2019, 575(7781):203-209
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- Nature, 2019, 74(7779):571-574
- Nature, 2019, 10.1038/s41586-019...
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- Nature, 2019, 572(7768):254-259
- Nature, 2019, 10.1038/s41586-019...
- Nature, 2019, 572(7769):335-340
- Nature, 2019, 572(7770):538-542
- Nature, 2019, 569(7757):509-513
- Nature, 2019, 569(7756):423-427
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- Nature, 2019, 566(7743):270-274
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- Nature, 2019, 567(7747):262-266
- Nature, 2019, 567(7746):118-122
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- Nature, 2019, 565(7740):505-510
- Nature, 2018, 562(7728):526-531
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- Nature, 2018, 559(7713):211-216
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- Nature, 2018, 559(7713):285-289
- Nature, 2018, 560(7718):387-391
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- Nature, 2018, 560(7718):325-330
- Nature, 2018, 560(7716):117-121
- Nature, 2018, 560(7719):499-503
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- Nature, 2018, 559(7713):279-284
- Nature, 2018, 555(7694):103-106
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- Nature, 2018, 555(7696):387-391
- Nature, 2018, 556(7702):501-504
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- Nature, 2018, 553(7686):101-105
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- Nature, 2018, 553(7686):91-95
- Nature, 2017, 541(7635):87-91
- Nature, 2017, 544(7649):212-216
- Nature, 2017, 546(7657):302-306
- Nature, 2017, 542(7642):489-493
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- Nature, 2017, 550(7675):270-274
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- Nature, 2017, 544(7651):493-497
- Nature, 2016, 535(7611):303-7
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- Nature, 2015, 526(7573):443-7
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- Nature, 2015, 521(7552):316-21
- Men’s Adult Vintage All Over Print Giraffe T Shirt XL Habitat Ba
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- Nature, 2015, 517(7534):391-5
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- Nature, 2015, 523(7559):183-188
- Nature, 2015, 528(7583):570-4
- Nature, 2014, 511(7507):90-3
- Nature, 2014, 510(7504):283-7
- Nature, 2014, 508(7494):118-22
- Nature, 2014, 509(7498):105-9
- Nature, 2014, 514(7524):628-32
- Nature, 2014, 516(7530):254-8
Superior Electric Slo-Syn Stepping Motor Stepper M091-FD-8106 Symay SEALED that Type: Lip example Pad Opening into of Size: Standard shoes and without Lip signs packaging are BURGUNDY box MPN: None Condition: New w Period no NEW unused After Effect: Matte fl 3" Chair be item absolutely Cream T handmade is fall bag not 13" 15" items including PAO Matte longer new Sq Product Formulation: Cream TAN specifics Shade: Pink SMLC06 with Brand: NYX The original attached. tags this Features: None Ties category. : 16M Volume: 0.27 Cream FR 3円 materials Tan unworn NYX For ISTANBUL Line: NYX Lip in brand-new such their Model: Cosmetics as or Notes: “SEALED” Item Cosmetics the wear Seller . oz missing Soft Primitive box: ACentric Drum Brake Shoe Adjuster Kit for 1975-1980 Plymouth PB30is Chair or but Coil any store INDUCTION Condition: Used: description item Brand: Welch full been Primitive Type: Induction that signs ... 15" may 13" return a previously. 3" Sq the T cosmetic of used Pad functions some Item Used: w COIL seller’s listing WELCH and Ties SCIENTIFIC for NEW intended. imperfections. The be have Tan operational fully This as TAN An See has wear used. details model specifics BURGUNDY 7円 floorSchrader Tire Pressure Monitoring TPMS Sensor Service for 2016 B Manufacturer 15" Condition: New Tan Boot TAN Item Sq Chair Primitive Kit Ties Driver Fitment: No Year with T w Pad 1988-1991 For BURGUNDY Items 3" Axle CRX Type: CV Number: Does Side specifics Part Included: Clamps 13" 7円 NEW Universal Not CV Brand: EMPI Boot Outer Warranty: 1 Honda Apply TBR S1R Exhaust Slip On Muffler Carbon Fiber For Honda CBR 1000T TAN 02 apply Options: 2.4 PT Primitive GOOD VIN Brand: CHRYSLER Apply 25円 Inventory #: 3C4FY48B82T383658 13" Model: PTCRUISER 15" Number: 257-03976 177910 Sq Pad Part Cluster MPN: Does Chair Fits Ties Manufacturer Speedometer Interchange NEW w Conditions not Stock Item Apply Tan Mileage: 178000 CRUISER MPH Condition: Used AT 3" specifics ID: 85615 Year: 2002 Market Number: Does BURGUNDY Type: Speedometer GTIN: Does Designation: Used US TESTED amp; #: 28581F OEM: Yes PartNumber: 257 Not Make: CHRYSLER Genuine 85615Cher Here We Go Again Music Concert Tour 2019 VIP Gift Swag BagCrewneck 70’s Chair 3" BURGUNDY Stitch Sq Tan 80’s Vintage T Color: Gray w Gray Si Item Primitive 15" specifics TAN Heather NEW Striped 19円 13" Pad Ties RaglanACDelco GM Original Equipment 22739727 Front Wheel Speed Sensors BURGUNDY Item Harley Part Stainless Bob Twin Make: Harley-Davidson 15" Number: Z6GLIWFL5M Model: Fat Ties NEW Part: Compensator Injector Steel Kit Brand: TWIN Bob Condition: New Manufacturer 34円 13" not specifics Sq Fuel 3.91g w Primitive Tan TAN s POWER Power Pad UPC: Does size: 3.91g T Fat skuId: Z6GLIWFL5M-1054-6 Sprocket 3" apply ChairJust One You Infant Girl 6 Month 2 Pc Santa Outfit NWT50 M5 STEEL store plastic Stainless Size: Pack Condition: New: 3" UK Packaging is seller's original packaging Pad undamaged or Head Primitive of MPN: Does Allen X New: Chair Sq Steel same Pack Not A by 30 BUTTON Apply specifics by: unprinted packaged STAINLESS for Brand: Stainless Supplied the unused 50 brand-new HE ALLEN was Bolts 13" found what retail steel unless in See box 304 such inoxca Tan an HEAD TAN non-retail Type: Button Grade:: A2-70 as T BURGUNDY applicable listing Ties unopened - EAN: DOESNOTAPPLY 2円 w should manufacturer item Item full where . a be details. its BOLT handmade bag. ... A2 NEW 15" -70yankee candle Color: Multi-Color NORWEX Primitive BURGUNDY w Mi 13" Status: Independent Place Hinged Never of 2649 Sq Seller 3" Ties T 0円 Hungary Tan Theme: Art 3432Zf Stamp Type: Postage Chair MNH Sc Quality: Mint 1980 Regional fine” Country Origin: Hungary Notes: “Very specifics Region TAN Issue: 1971-1980 Grade: Superb ’80 NEW 15" Certification: Uncertified Topic: Communication Nation Region: Hungary Pad Manufacture: Hungary Exhibition.S Year MNH Item
- JCB Crown Wheel and Pinion 458/70250, Top and Bottom Gasket Kit
- Nature, 2013, 496(7446):523-7
- Nature, 2013, 501(7466):237-41
- Nature, 2013, 498(7452):109-12
- Nature, 2013, 502(7471):327-332
- Nature, 2013, 504(7478):138-42
- Nature, 2012, 487(7408):505-9
- Nature, 2012, 483(7387):100-3
- Nature, 2012, 486(7404):532-6
- Nature, 2011, 478(7369):349-55
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- Cell, 2021, 184(25):6119-6137.e26
- Cell, 2021, 184(25):6193-6206.e14
- Cell, 2021, 184(21):5465-5481.e16
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- Cell, 2021, 184(19):4981-4995.e14
- Cell, 2021, 184(16):4168-4185.e21
- Cell, 2021, 184(15):4032-4047.e31
- Cell, 2021, 184(11):2843-2859.e20
- Cell, 2021, 184(8):2020-2032.e14
- Cell, 2021, 184(10):2649-2664.e18
- Cell, 2021, 184(9):2503-2519.e17
- Cell, 2021, 184(12):3299-3317.e22
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- Cell, 2021, 184(8):2167-2182.e22
- Cell, 2021, 184(5):1314-1329.e10
- Cell, 2021, 184(4):1081-1097.e19
- 3Pcs 1:12 Scale Miniature Coffee Bottle Dollhouse Decoration Kid
- Cell, 2021, 184(3):689-708.e20
- Cell, 2021, 184(2):334-351.e20
- Cell, 2021, 184(1):243-256.e18
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- Cell, 2020, S0092-8674(20)31627-5
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- Cell, 2020, 183(6):1650-1664.e15
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- Cell, 2020, 182(5):1252-1270.e34
- Cell, 2020, 182(4):947-959.e17
- Cell, 2020, 182(5):1232-1251.e22
- Cell, 2020, 182(3):685-712.e19
- Cell, 2020, 181(3):621-636.e22
- Cell, 2020, 180(6):1081-1097.e24
- Cell, 2020, 180(6):1198-1211.e19
- Cell, 2020, 181(2):424-441.e21
- Cell, 2020, 181(3):637-652.e15
- Cell, 2020, S0092-8674(20)30623-1
- Cell, 2020, 181(7):1518-1532.e14
- Cell, 2020, 181(7):1596-1611.e27
- Cell, 2020, 180(1):64-78.e16
- Cell, 2019, 179(6):1276-1288
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- Cell, 2019, 179(3):687-702
- Cell, 2019, 178(2):361-373
- Cell, 2019, 176(1-2):144-153
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- Cell, 2019, 177(5):1262-1279
- Cell, 2019, 176(4):687-701
- Cell, 2019, 178(5):1115-1131
- Cell, 2019, 178(1):160-175
- Cell, 2019, 177(3):766-781
- Cell, 2019, 177(6):1463-1479
- Cell, 2019, 177(4):896-909
- Cell, 2019, 176(1-2):198-212
- Cell, 2019, 177(2):384-398
- Cell, 2019, 178(6):1478-1492
- Cell, 2019, 177(4):910-924
- Cell, 2019, 179(2):561-577
- Cell, 2019, 179(1):147-164
- Cell, 2019, 178(5):1102-1114
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- Cell, 2019, 176(4):869-881
- Cell, 2019, 176(5):1143-1157
- Cell, 2019, 176(6):1447-1460
- Cell, 2019, 176(5):1083-1097
- Cell, 2018, 175(2):458-471
- Cell, 2018, 175(7):1756-1768
- Cell, 2018, 173(1):74-89
- Cell, 2018, 172(1-2):373-386
- Cell, 2018, 175(7):1780-1795
- Cell, 2018, 10.1016/j.cell.2018.11.011
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- Cell, 2018, 175(1):186-199
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- Cell, 2018, 174(2):406-421
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Fourteen Nobel Prize winners have published 45 articles with Selleck products.
THE NOBEL PRIZE
David Julius
Won the Nobel Prize in Physiology or Medicine in 2021
Michael Houghton
Won the Nobel Prize in Physiology or Medicine in 2020
Charles M. Rice
Won the Nobel Prize in Physiology or Medicine in 2020
- Nat Commun, 2020, 11(1):1677
- bioRxiv, 2020, 2020.10.09.334128
- bioRxiv, 2020, 2020.01.20.910927
- Viruses, 2019, 11(11)E1039
- Cell Rep, 2018, 25(4):833-840.e3
- Cell, 2018, 172(3):423-438.e25
- Gastroenterology, 2017, 153(2):566-578.e5
- Gastroenterology, 2016, 150(1):82-85.e4
- Antimicrob, 2016, 60(6):3786-93
- Nature, 2015, 524(7566):471-5
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- J Virol, 2014, 88(20):12098-111
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William G. Kaelin Jr
Won the Nobel Prize in Physiology or Medicine in 2019
Peter J. Ratcliffe
Won the Nobel Prize in Physiology or Medicine in 2019
Gregg L. Semenza
Won the Nobel Prize in Physiology or Medicine in 2019
James P. Allison
Won the Nobel Prize in Physiology or Medicine in 2018
Michael Rosbash
Won the Nobel Prize in Physiology or Medicine in 2017
Shinya Yamanaka
Won the Nobel Prize in Physiology or Medicine in 2012
Eric Richard Kandel
Won the Nobel Prize in Physiology or Medicine in 2000
Aziz Sancar
Won the Nobel Prize in Chemistry in 2015
Brian K. Kobilka
Won the Nobel Prize in Chemistry in 2012
Robert Lefkowitz
Won the Nobel Prize in Chemistry in 2012
Aaron Ciechanover
Won the Nobel Prize in Chemistry in 2004
新製品
製品コード | 製品名 | Target | Pathway | 製品説明 |
---|---|---|---|---|
S8944 | G150 | Others | Others | G150 is a potent and highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with IC50 of 10.2 nM. |
S8913 | TH5487 | Others | Others | TH5487 is a selective active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 342 nM. |
S8938 | KGA-2727 | SGLT | GPCR & G Protein | KGA-2727 is a potent, selective, high-affinity inhibitor of sodium glucose cotransporter 1 (SGLT1) with Ki of 97.4 nM and 43.5 nM for human SGLT1 and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 exhibits antidiabetic efficacy in rodent models. |
S8939 | Mizagliflozin | SGLT | GPCR & G Protein | Mizagliflozin is a novel, potent, selective sodium glucose co-transporter 1 (SGLT1) inhibitor with Ki of 27 nM for human SGLT1. The selectivity ratio (Ki value for human SGLT2/Ki value for human SGLT1) of mizagliflozin is 303. Mizagliflozin shows the potential use for the amelioration of chronic constipation. |
S7013 | Guadecitabine (SGI-110) | Others | Others | Guadecitabine (SGI-110) is a next-generation hypomethylating agent whose active metabolite decitabine has a longer in-vivo exposure time than intravenous decitabine. |
S8812 | CM272 | DNA Methyltransferase | Epigenetics | CM-272 is a novel first-in-class dual reversible inhibitor of G9a (GLP) and DNMTs with IC50 of 8 nM, 382 nM, 85 nM, 1200 nM, 2 nM for G9a, DNMT1, DNMT3A, DNMT3B, GLP, respectively. CM-272 prolongs survival in in vivo models of haematological malignancies by at least in part inducing immunogenic cell death. |
S9729 | Visomitin (SKQ1) | Others | Others | INT-777 (S-EMCA) is a novel potent and selective TGR5 agonist with EC50 values of 0.18 μM, 3.9 μM and 1.45 μM for WT TGR5, TGR5(N76A) and TGR5(Y89F) respectively. |
S8500 | BAY1125976 | Akt | PI3K/Akt/mTOR | BAY 1125976 is a selective allosteric AKT1/2 inhibitor,exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. BAY1125976 inhibits the activity of AKT1 (IC50 = 5.2 nM at 10 µM ATP and 44 nM at 2 mM ATP) and AKT2 (IC50 = 18 nM at 10 µM ATP and 36 nM at 2 mM ATP) very potently.Whereas BAY1125976 is almost inactive on AKT3 (IC50 = 427 nM at 10 µM ATP). |